Instituto de Recursos Cinegéticos
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El IREC es el primer centro científico español dedicado a la investigación de diversos aspectos relativos a la caza, entendida ésta como un recurso natural renovable. El IREC fue creado el 24 de febrero de 1999 mediante un convenio específico entre el CSIC, la UCLM y la JCCM. Se trata por tanto, de un Instituto Mixto de titularidad compartida entre estas tres instituciones, las cuales se encuentran representadas en los órganos de gobierno del Instituto a través de la Comisión Rectora, quien entre sus funciones ostenta la de apoyar al IREC ante otras Instituciones y Entidades, a fin de conseguir lo necesario para el mejor funcionamiento y promoción del Instituto.
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CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation
(Springer, 2022-11)Purpose: Most monotherapies available against glioblastoma multiforme (GBM) target individual hallmarks of this aggressive brain tumor with minimal success. In this article, we propose a therapeutic strategy using coenzyme ... -
Good and bad get together: Inactivation of SARS-CoV-2 in particulate matter pollution from different fuels
(Elsevier, 2022-07)Air pollution and associated particulate matter (PM) affect environmental and human health worldwide. The intense vehicle usage and the high population density in urban areas are the main causes of this public health impact. ... -
One Health Approach to Identify Research Needs on Rhipicephalus microplus Ticks in the Americas
(MDPI, 2022-10)We aim to provide a harmonized view of the factors that affect the survival and promote the spread of R. microplus in the Neotropics, approaching its different facets of biology, ecology, distribution, and control. We ... -
Monitoring the Subolesin Vaccine Field Trial for Safer Control of Cattle Ticks Amidst Increasing Acaricide Resistance in Uganda
(MDPI, 2022-09)A collaboration program was established between the group of Health and Biotechnology (SaBio) of the IREC Institute of Game and Wildlife Research (CSIC-UCLM-JCCM, Spain) and the National Agricultural Research Organization ... -
Differentially represented proteins in response to infection with Mycobacterium tuberculosis identified by quantitative serum proteomics in Asian elephants
(MDPI, 2022-09)Tuberculosis is a major global concern. Tuberculosis in wildlife is a risk for zoonotic transmission and becoming one of the challenges for conservation globally. In elephants, the number of cases is likely rising. The ... -
Correlates with Vaccine Protective Capacity and COVID-19 Disease Symptoms Identified by Serum Proteomics in Vaccinated Individuals
(MDPI, 2022-09)In the last two years, the coronavirus disease 19 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a scientific and social challenge worldwide. Vaccines have been the ... -
The Correlation between Subolesin-Reactive Epitopes and Vaccine Efficacy
(MDPI, 2022-08)Vaccination is an environmentally-friendly alternative for tick control. The tick antigen Subolesin (SUB) has shown protection in vaccines for the control of multiple tick species in cattle. Additionally, recent approaches ... -
HEPA filters of portable air cleaners as a tool for the surveillance of SARS-CoV-2
(Wiley, 2022-08)Studies about the identification of SARS-CoV-2 in indoor aerosols have been conducted in hospital patient rooms and to a lesser extent in nonhealthcare environments. In these studies, people were already infected with ... -
Art–science multidisciplinary collaborations to address the scientific challenges posed by COVID-19
(Taylor and Francis, 2022-09)The ongoing coronavirus pandemic COVID-19 constitutes a scientific and social challenge. The application of mixed-methods research with multidisciplinary collaborations increases the success of experimental design and ... -
Current and Future Strategies for the Diagnosis and Treatment of the Alpha-Gal Syndrome (AGS)
(Taylor and Francis Group, 2022-07)The α-Gal syndrome (AGS) is a pathognomonic immunoglobulin E (IgE)-mediated delayed anaphylaxis in foods containing the oligosaccharide galactose-α-1,3-galactose (α-Gal) such as mammalian meat or dairy products. Clinical ... -
Heat inactivated mycobacteria, alpha-Gal and zebrafish: Insights gained from experiences with two promising trained immunity inductors and a validated animal model
(Wiley, 2022-06)Trained immunity (TRAIM) may be defined as a form of memory where innate immune cells such as monocytes, macrophages, dendritic and natural killer (NK) cells undergo an epigenetic reprogramming that enhances their primary ... -
The Impact of RNA Interference in Tick Research
(MDPI, 2022-07)Over the past two decades, RNA interference (RNAi) in ticks, in combination with omics technologies, have greatly advanced the discovery of tick gene and molecular function. While mechanisms of RNAi were initially ... -
Understanding Mycobacterium tuberculosis complex in elephants through a One Health approach: a systematic review
(BMC, 2022-07)Background: Mycobacterium tuberculosis complex (MTC) that causes the chronic infectious disease- tuberculosis (TB), often presents with a complicated epidemiological pattern where the transmission chain may include humans, ... -
Functional characterization of α-Gal producing lactic acid bacteria with potential probiotic properties
(Nature Research, 2022-05)The possibility of exploiting the human immune response to glycan α-Gal for the control of multiple infectious diseases has been the objective of recent investigations. In this field of research, the strain of Escherichia ... -
Assessment of the safety and efficacy of an oral probiotic-based vaccine against Aspergillus infection in captive-bred Humboldt penguins (Spheniscus humboldt).
(Frontiers Media, 2022-05)Aspergillosis is a fungal infection caused mainly by Aspergillus fumigatus that often results in respiratory disease in birds. Aspergillosis is a major cause of morbidity and mortality in captive-bred penguin species. ... -
Akirin/Subolesin regulatory mechanisms at host/tick–pathogen interactions
(Oxford University Press, 2021-11)Ticks and tick-borne pathogens such as Anaplasma phagocytophilum affect human and animal health worldwide and thus the characterization of host/tick–pathogen interactions is important for the control of tick-borne diseases. ... -
Exploring the ecological implications of microbiota diversity in birds: natural barriers against avian malaria
(Frontiers Media, 2022-02)Natural antibodies (Abs), produced in response to bacterial gut microbiota, drive resistance to infection in vertebrates. In natural systems, gut microbiota diversity is expected to shape the spectrum of natural Abs and ... -
Low NETosis Induced in Anaplasma phagocytophilumInfected Cells
(MDPI, 2022-10-20)Anaplasma phagocytophilum are obligatory intracellular bacteria that preferentially replicate inside leukocytes by utilizing biological compounds and processes of these primary host defensive cells. In this study, ... -
A study of viral pathogens in bat species in the Iberian Peninsula: identification of new coronavirus genetic variants
(Taylor & Francis, 2022-11-03)Bats have long been associated with multiple pathogens, including viruses affecting humans such as henipaviruses, filoviruses, bunyaviruses and coronaviruses. The alpha and beta coronaviruses genera can infect most mammalian ... -
Plasticity in daily activity patterns of a key prey species in the Iberian Peninsula to reduce predation risk
(CSIRO Publishing, 2021-04-09)Context. Some prey species can shift their daily activity patterns to reduce the risk of encountering predators, and, in turn, predators develop strategies to increase their chances of meeting prey. European rabbit ...
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