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Increased blood cholesterol after a high saturated fat diet is prevented by aerobic exercise training

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dc.contributor.author Mora-Rodríguez, Ricardo
dc.contributor.author Ortega, Juan Fernando
dc.contributor.author Fernandez-Elias, Valentín Emilio
dc.contributor.author Hamouti, Nassim
dc.date.accessioned 2018-04-19T10:55:50Z
dc.date.available 2018-04-19T10:55:50Z
dc.date.issued 2013
dc.identifier.citation Applied Physiology Nutrition and Metabolism-Physiologie appliquee nutrition et metabolisme. 2013, (38), 42-48 es_ES
dc.identifier.uri http://hdl.handle.net/10578/17194
dc.description.abstract A high saturated fatty acids diet (HSFAD) deteriorates metabolic and cardiovascular health 3 while aerobic training improves them. The aim of this study was to investigate in physically 4 inactive, overweight people if two weeks of HSFAD leads to hyperlipemia or insulin resistance 5 and if concurrent aerobic exercise training counteracts those effects. Fourteen overweight (BMI: 27.5±0.6 kg·m-26 ) healthy-young individuals (24.8±1.8 yr old) were randomly assigned to 7 a diet (D) or a diet plus exercise (D+E) group. During 14 consecutive days both groups increased dietary saturated fatty acids from 31±10 to 52±14 g·day-1 8 (P<0.001) while 9 maintaining total fat intake. Concurrent to the diet, the D+E group underwent 11 cycleergometer sessions of 55 min at 60% 2peak O · 10 V . Before and after intervention insulin sensitivity 11 was estimated and body composition, plasma lipid profile, free fatty acids (FFA) composition, resting blood pressure (BP) and 2peak O · 12 V were measured. Body weight and composition, 13 plasma FFA composition and insulin sensitivity remained unchanged in both groups. 14 However, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) increased above pre-intervention values in the D group (147±8 to 161±9 mg·dL-115 , P=0.018 and 71±10 to 82±10 mg·dL-116 , P=0.034, respectively). In contrast, in the D+E group, TC and LDL-C remained unchanged (153±20 to 157±24 mg·dL-1 and 71±21 to 70±25 mg·dL-117 ). Additionally the D+E group lowered systolic BP (6±2 mmHg, P=0.029) and increased 2peak O · V (6±2 ml·kg-1·min-118 , 19 P=0.020). Increases in TC and LDL-C induced by 14 days of HSFAD can be prevented by 20 concurrent aerobic exercise training that in addition improves cardio-respiratory fitness. es_ES
dc.format text/plain es_ES
dc.language.iso en es_ES
dc.publisher NRC Researh Press es_ES
dc.rights info:eu-repo/semantics/openAccess es_ES
dc.subject Exercise training es_ES
dc.subject Exercise es_ES
dc.subject LDL es_ES
dc.subject Atherogenic diet es_ES
dc.subject Insulin resistance es_ES
dc.subject OGTT es_ES
dc.subject Entrenamiento deportivo es_ES
dc.subject Ejercicio es_ES
dc.subject Dieta aterogénica es_ES
dc.subject Resistencia a la insulina es_ES
dc.title Increased blood cholesterol after a high saturated fat diet is prevented by aerobic exercise training es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.identifier.DOI https://doi.org/10.1139/apnm-2012-0123


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