Recent Submissions

  • Subchronic Graphene Exposure Reshapes Skin Cell Metabolism 

    Frontiñán, Javier; Llanos-González, Emilio; González, Viviana Jehová; Vázquez, Ester; Durán Prado, Mario (ACS, 2022-05)
    In recent years, the toxicity of graphene-related materials (GRMs) has been evaluated in diverse models to guarantee their safety. In most applications, sublethal doses of GRMs contact human barriers such as skin in a ...
  • Rapid and efficient testing of the toxicity of graphene-related materials in primary human lung cells 

    Frontiñán, Javier; Jehová González, Viviana; Vázquez, Ester; Durán Prado, Mario (Nature, 2022-05)
    Graphene and its derivative materials are manufactured by numerous companies and research laboratories, during which processes they can come into contact with their handlers' physiological barriers—for instance, their ...
  • A comprehensive systematic review of CSF proteins and peptides that defne Alzheimer’s disease 

    Pedrero Prieto, Cristina M.; García-Carpintero Fernández-Pacheco, Sonia; Frontiñán, Javier; Llanos González, Emilio; Aguilera García, Cristina; Alcaín, Francisco Javier; Lindberg, Iris; Durán Prado, Mario; Peinado Reina, Juán Ramón; Rabanal Ruiz, Yoana (BMC, 2020-06-05)
    Background: During the last two decades, over 100 proteomics studies have identifed a variety of potential bio‑ markers in CSF of Alzheimer’s (AD) patients. Although several reviews have proposed specifc biomarkers, to ...
  • Human ß-amyloid enriched extracts: evaluation of in vitro and in vivo internalization and molecular characterization. 

    Cristina M Pedrero Prieto; Alicia Flores-Cuadrado; Daniel Saiz; Isabel Úbeda Bañón; Javier Frontiñán; Francisco Javier Alcain; Lourdes Mateos-Hernández; José de la Fuente; Mario Durán-Prado; Margarita M. Villar-Rayo; Alino Martínez-Marcos; Juan Ramón Peinado-Mena (BioMed Central Ltd., 2019-06-29)
    BACKGROUND: Intracerebral inoculation of extracts from post-mortem human Alzheimer's disease brains into mice produces a prion-like spreading effect of amyloid-ß. The differences observed between these extracts and the ...
  • Graphene and graphene oxide induce ROS production in human HaCaT skin keratinocytes. 

    Marco Pelin; Laura Fusco; Cristina Martín Jiménez; Silvio Sosa; Javier Frontiñan; Jose Miguel Gonzalez-Dominguez; Mario Durán-Prado; Ester Vázquez; Maurizio Prato; Aurelia Tubaro (Royal Society of Chemistry, 2018-07-07)
    The extraordinary physicochemical properties of graphene-based nanomaterials (GBNs) make them promising tools in nanotechnology and biomedicine. Considering the skin contact as one of the most feasible exposure routes to ...